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The Twenty Minute VC

OpenAI & SpaceX S1 Drops | Anthropic Laps OpenAI at $44B ARR | Nvidia Prints $81.6B | Layoffs at Cloudflare & ClickUp

1h 27m · Transcribed via assemblyai · Watch on YouTube

20VC roundtable (Harry Stebbings + Rory O'Driscoll + Jason). The single densest market-recap of the week. **OpenAI confidentially files its S1; SpaceX drops the largest IPO in history; Anthropic hits $44B ARR and laps OpenAI in revenue; Nvidia prints $81.6B revenue.** The roundtable's spine is the **bull-vs-bear case on Anthropic** and the **ROI-on-AI-spend reckoning**. Bull: Anthropic *'did as much in Q1 as all of last year'*, gross margins expanded **38% → 70%**, a **$559M operating profit projected for Q2**, Pareto-dominant on growth/profitability/scale. Bear: Claude is **2x the price of its competitor** and that premium may not hold once enterprises optimise token budgets (mix GPT-4-class + Sonnet + DeepSeek); **the Uber COO says a full year's Anthropic credits were spent in four months with gains 'not measurable'; Microsoft is reportedly moving off Anthropic because Opus is too expensive.** On Nvidia: **$50-56B profit in the quarter — 'the most profitable company on the planet'** (~$200B/yr run-rate), $81.6B revenue (+80%), $91B Q2 guide, $80B buyback; stock flat because *'the stock moves on the Delta news, not the total news'*. Jensen's **$3-4T AI-capex-by-2030** call frames the $64-trillion question: is the ROI there on the next $2T? Valuation skepticism is loud — *'100x trailing sales... SolarCity on steroids... the GeoCities deal of the AI era... I wouldn't buy a share'* — but **'the picks and shovels of the agentic revolution is just a good place to be.'** Plus: Cloudflare + ClickUp layoffs and the over-hiring-vs-AI-efficiency debate (Andreessen's 'overhiring during COVID' take called 'the dumbest take').

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Notable quotes

Anthropic has done as much in Q1 as all of last year. Within a couple of quarters, Anthropic will be visibly and obviously ahead, profitable, growing more quickly and bigger. That's Pareto dominant on all three vectors this week.

Rory O'Driscoll · 0:00

Gross margins expanded from 38% to 70% and they're going to have a $559 million operating profit in Q2 projected. High growth and improving margins meant profits were inevitable.

Rory O'Driscoll · 11:20

Claude is twice the price of its competitor. If even half the world says the ROI isn't there for a premium product, either it has to cut its prices to match the competition or it maintains the premium like Apple but won't be able to maintain its market share.

Rory O'Driscoll · 15:20

It's not the 81 billion in revenue, it's the 50-something billion in profits, which makes it the most profitable company on the planet. If that continued all year that's $200 billion of profit a year.

Rory O'Driscoll · 3:20

There has to be an ROI on that next 2 trillion. The $64 trillion question is, does that growth continue or do you start to hit not technical, but economic constraints.

Rory O'Driscoll · 5:40

100 times trailing sales, my God. I love the S1, but I think it's all madness. I wouldn't buy a share. It's SolarCity on steroids and we're all here for it because we love AI. But it makes no sense.

Jason · 1:00

When you go from experimental to we spent $300 million on tokens, you get some lift in efficiency, but that means $200 million of OPEX you didn't expect, and you have to terminate a whole bunch of people. At that point HR comes in.

Rory O'Driscoll · 18:20

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