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All-In Podcast

Pope vs AI, Anthropic's Digital God, AI Job Loss Narrative Flips, Open Source Wars

1h 34m · Transcribed via assemblyai · Watch on YouTube

Sacks + Chamath + Jason + **Bill Gurley guest-hosting for Friedberg**. Four threads. **(1) Pope Leo XIV's first encyclical — 'Magnifica Humanitas', 235 pages / 42,000 words on AI.** Warns technology 'takes on the characteristics of those who build, finance and control it', calls for AI regulation, a ban on autonomous weapons, worker-retraining guardrails. Lobbied by Google/Amazon/Meta on April 29 to soften it — he was not swayed. Sacks agrees the biggest risk is centralisation of power but argues *government* is the likely culprit, not a private actor; warns against an 'FDA for AI'. **(2) The Anthropic critique — Gurley's 'Dr Frankenstein theory'.** Gurley: Anthropic is the only company that leads its field AND is its own most negative commenter. After reading everything he could for 30 days, he moved off the pure regulatory-capture thesis to: *'I don't think they think they're writing software. I think they're midwifing a deity.'* Built on Dario's 'Machines of Loving Grace' (a capitalist economy of AI systems that allocate resources to humans) + Chris Olah's 80-page constitution + Amanda Askell as 'chief philosopher'. Chamath's game-theory overlay: get three or four entities in a room, dominate them, set the rules the referees can't understand. **(3) Model commoditisation + enterprise reality.** Rogo's eval: *'There is no single best model anymore'* — Opus 4.7, GPT-5.5, Sonnet 4.6 separated by <0.3pp. Raises the ROI-on-training question. **Microsoft killing Claude licenses; Kirkland & Ellis spending $500M on its own frontier model; a Fortune-20 CEO asked for $1B in AI opex savings, team spent $200M on tokens with minimal results.** Claude for Excel 'better than Copilot by a lot'. **(4) The AI-job-loss vibe shift** — Sam + Dario walking it back, Goldman CEO, explosion in job postings; a securities lawyer warning 'AI washing' could be securities fraud (Wix layoff memo cited). Open-source/open-weight ban breadcrumbs (Sacks) — and the paradox that China leads the open-weight movement while the US centralises. **Apple as the dark-horse 'intelligence sovereignty' play** (M5, 48-128GB, Mac Studio terabyte). Elon's training-complex rewrite in C — claimed order-of-magnitude speed-up vs JAX on 220k GPUs, pushing toward $10M training runs vs $10B.

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Notable quotes

I don't think they think they're writing software. I think they're midwifing a deity here. And I don't know which one I'm more afraid of, the regulatory capture or this second theory I call the Dr. Frankenstein theory.

Bill Gurley · 29:00

There is no single best model anymore. At the top of the leaderboard Opus 4.7, GPT 5.5, Sonnet 4.6 appear almost indistinguishable, separated by less than 3/10 of a percentage point.

Chamath Palihapitiya · 40:00

If you want to be unexploitable, the best thing you could do if you're trying to build a super god is have three or four entities in a room, close the door behind you, and then dominate those other three or four entities. And then you set the rules. Because the referees don't understand the game.

Chamath Palihapitiya · 34:40

Overheard from a Fortune 20 company: CEO asked for a billion in AI generated opex savings at the beginning of the year. So we're six months in, the team has spent $200 million on tokens with minimal results.

Jason Calacanis · 45:00

Claude for Excel is better than Copilot, not by a little, by a lot. Anyone that's going to run against them, they are a worthy foe.

Bill Gurley · 46:00

Our adversary, the Chinese, of all people, the Communist Party, is leading the open source movement and the United States is centralizing.

Jason Calacanis · 34:10

Elon was like, we've rewritten the entire training complex in C and it's an order of magnitude increase and we can run it on 220,000 GPUs. Why would we stick to the big $10 billion training runs when we can have the $10 million training runs?

Chamath Palihapitiya · 39:40

There's no scenario where you just do more for less and all of a sudden everyone has 70% operating margins. Someone else is going to come along and do more for less and lower the price.

Bill Gurley · 1:26:40

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